Doyle, Frank Conroy, Ronán McGee, Hannah Delaney, Mary Depressive symptoms in persons with acute coronary syndrome: specific symptom scales and prognosis <p>Objective To determine which particular depressive symptom scales, derived from three scales, predicted poorer prognosis in persons with acute coronary syndrome (ACS). Methods Hospitalised ACS patients (n=408) completed questionnaires (depression, vital exhaustion). Mokken scaling derived unidimensional scales. Major cardiac events (cardiac mortality, ACS, unplanned revascularisation) were assessed at median 67 weeks post-event. Results Only depressive symptoms of fatigue-sadness predicted prognosis in univariate (hazard ratio [HR]=1.8, 95% CI 1.1–3.0, p=0.025) and multivariate analysis (HR=1.8, 95% CI 1.1–2.9, p=0.025). Symptoms of anhedonia (HR=1.6, 95% CI 0.9–2.8, p=0.102) and depressive cognitions (HR=1.3, 95% CI 0.7–2.2, p=0.402) did not. Conclusion Symptoms of fatigue-sadness, but not other symptoms, were associated with increased risk of major cardiac events. Depression should be considered as a multidimensional, rather than a unidimensional, entity when designing interventions.</p> Depression;Acute coronary syndrome;Mokken scaling;Item response theory;Prognosis;Myocardial infarction;Psychology and Cognitive Sciences not elsewhere classified 2019-11-22
    https://repository.rcsi.com/articles/journal_contribution/Depressive_symptoms_in_persons_with_acute_coronary_syndrome_specific_symptom_scales_and_prognosis/10773980