10779/rcsi.10991345.v1
Harrison C. Daly
Harrison C.
Daly
Gonzalo Sampedro
Gonzalo
Sampedro
Corentin Bon
Corentin
Bon
Dan Wu
Dan
Wu
Ghazi Ismail
Ghazi
Ismail
Ronan A. Cahill
Ronan A.
Cahill
Donal F. O'Shea
Donal F.
O'Shea
BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential.
Royal College of Surgeons in Ireland
2019
Aza Compounds
Boron Compounds
Colon
Dose-Response Relationship
Drug
Fluorescent Dyes
Humans
Molecular Structure
Porphobilinogen
Spectroscopy
Near-Infrared
Structure-Activity Relationship
2019-11-23 11:49:26
Journal contribution
https://repository.rcsi.com/articles/journal_contribution/BF2-azadipyrromethene_NIR-emissive_fluorophores_with_research_and_clinical_potential_/10991345
<p>The use of near-infrared fluorescence for in vivo research and intraoperative clinical imaging is rapidly expanding, with new applications being proposed and developed. While imaging hardware and software have significantly progressed in recent times, the molecular fluorescent agents remain a limiting factor. In this report, the design, synthesis, photophysical characterization and bio-medical imaging assessment of two new NIR-fluorophores based on the BF</p>