Bu4N(+) Alkoxide-InitiatedAutocatalytic Addition Reactions with.pdf (1.08 MB)
Bu4N(+) Alkoxide-Initiated/Autocatalytic Addition Reactions with Organotrimethylsilanes.
Version 2 2022-03-10, 14:44
Version 1 2019-11-23, 11:50
journal contribution
posted on 2019-11-23, 11:50 authored by Manas Das, Donal F. O'SheaThe use of Me3SiO(-)/Bu4N(+) as a general activator of organotrimethylsilanes for addition reactions has been established. The broad scope of the method offers trimethylsilanes (including acetate, allyl, propargyl, benzyl, dithiane, heteroaryl, and aryl derivatives) as bench-stable organometallics that can be readily utilized as carbanion equivalents for synthesis. Reactions are achieved at rt without the requirement of specialized precautions that are commonplace for other organometallics.
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European Research Association ERA-Chemistry and the Irish Research Council (IRC).
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This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/jo5007637Published Citation
Das M, O'Shea DF. Bu4N(+) Alkoxide-Initiated/Autocatalytic Addition Reactions with Organotrimethylsilanes. Journal of Organic chemistry. 2014;79(12):5595-607.Publication Date
2014-06-20Publisher
American Chemical SocietyExternal DOI
PubMed ID
24841115Usage metrics
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CatalysisCations/*chemistryMolecular StructureOrganometallic Compounds/*chemical synthesis/*chemistryOrganosilicon Compounds/*chemical synthesis/chemistryQuaternary Ammonium Compounds/*chemical synthesis/*chemistryQuinolizines/*chemistrySulfur Compounds/*chemistryTrimethylsilyl Compounds/*chemical synthesis/*chemistry
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