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Childhood psychotic experiences are associated with poorer global.pdf (348.58 kB)

Childhood psychotic experiences are associated with poorer global functioning throughout adolescence and into early adulthood.

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Version 2 2022-03-21, 12:36
Version 1 2019-11-22, 17:10
journal contribution
posted on 2019-11-22, 17:10 authored by Colm Healy, Donal Campbell, Helen Coughlan, Mary Clarke, Ian Kelleher, Mary Cannon

BACKGROUND: Psychotic experiences (PEs) are common in childhood and have been associated with concurrent mental disorder and poorer global functioning. Little is known about the effects of childhood PEs on future functioning. We investigated the effects of childhood PEs on global functioning from childhood into early adulthood.

METHOD: Fifty-six participants from a community sample completed all three waves of the Adolescent Brain Development study (T1x¯ Age: 11.69, T2x¯ Age: 15.80 T3x¯Age: 18.80). At each phase, participants completed a clinical interview assessing for PEs, mental disorder and global function. Repeated measures models, adjusted for mental disorder and gender, were used to compare current (C-GAF) and most severe past (MSP-GAF) functioning in participants who had reported PEs in childhood and controls.

RESULTS: Participants with a history of PEs had significantly poorer C-GAF (P < 0.001) and MSP-GAF scores (P < 0.001). Poorer functioning was evident in childhood (C-GAF: P = 0.001; MSP-GAF: P < 0.001), adolescence (C-GAF: P < 0.001; MSP-GAF: P = 0.004) and early adulthood (C-GAF: P = 0.001; MSP-GAF: P = 0.076).

DISCUSSION: Children who report PEs have persistently poorer functioning through to early adulthood. The longitudinal association between childhood PEs and global functioning highlights the underlying global vulnerability in children reporting PEs, beyond what can be explained by mental disorder.

Funding

European Research Council (Grant Code 724809 iHEAR). Health Research Board (HRA-PHR-2015-1323).

History

Comments

This is the pre-peer reviewed version of the following article: Healy C, Campbell D, Coughlan H, Clarke M, Kelleher I, Cannon M. Childhood psychotic experiences are associated with poorer global functioning throughout adolescence and into early adulthood. Acta Psychiatrica Scandinavica. 2018;138(1):26-34, which has been published in final form at DOI: 10.1111/acps.12907This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

Published Citation

Healy C, Campbell D, Coughlan H, Clarke M, Kelleher I, Cannon M. Childhood psychotic experiences are associated with poorer global functioning throughout adolescence and into early adulthood. Acta Psychiatrica Scandinavica. 2018;138(1):26-34

Publication Date

2018-07-01

Publisher

Munksgaard International Publishers

PubMed ID

29855047

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