Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome.
BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer.
CASE PRESENTATION: Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well.
CONCLUSION: Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here.
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This article is also available from www.biomedcentral.comPublished Citation
Walsh DJ, Sills ES, Shkrobot LV, Gleeson NC, Sheppard MN, Walsh AP. Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome. World Journal of Surgical Oncology. 2009;7:46.Publication Date
2009-05-14External DOI
PubMed ID
19442277Department/Unit
- Obstetrics and Gynaecology