Dataset of mouse hippocampus profiled by LC-MSMS for label-free.pdf (150.91 kB)

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation.

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posted on 22.11.2019, 17:07 by Jane A. English, Caitriona Scaife, Akiko Harauma, Melanie Föcking, Kieran Wynne, Gerard Cagney, Toru Moriguchi, David R. Cotter

This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

Funding

David R. Cotter is funded by the Health Research Board, Clinical Scientist Award. Ger Cagney is funded by Science Foundation Ireland.

History

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The original article is available at www.sciencedirect.com

Published Citation

English JA, Scaife C, Harauma A, Focking M, Wynne K, Cagney G, Moriguchi T, Cotter DR. Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation. Data in Brief. 2016;7:341-3.

Publication Date

15/06/2016

Publisher

Elsevier

PubMed ID

26977433

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