The INCATM (Inhaler Compliance AssessmentTM): A comparison with e.pdf (585.05 kB)

The INCATM (Inhaler Compliance AssessmentTM): A comparison with established measures of adherence.

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posted on 22.11.2019, 15:43 by Catherine Moran, Frank Doyle, Imran Sulaiman, Kathleen Bennett, Garrett Greene, Gerard J. Molloy, Richard B. Reilly, Richard W. Costello, Lisa Mellon

Objective: To compare the Inhaler Compliance AssessmentTM (INCATM), a novel audio-recording device objectively measuring timing and proficiency of inhaler use, against established adherence measures, and explore its discriminant and predictive validity.

Design: Prospective observational study; 184 chronic obstructive pulmonary disease (COPD) patients used an INCATM-enabled salmeterol/fluticasone inhaler for one-month post-hospital discharge.

Main outcome measures: INCATM (Attempted, Attempted Interval, Actual) adherence correlated with Doses Used Rate, self-reported adherence and prescription refill for concurrent validity. Discriminant validity for reason for admission, cognition and lung function; predictive validity for health status and quality-of-life.

Results: Rates of Attempted, Attempted Interval and Actual adherence were 59, 47 and 23%, respectively. Only 7% of participants had Actual adherence >80%. INCATM variables significantly correlated with Doses Used Rate but not with self-report; Attempted and Attempted Interval were weakly associated with prescription refill. Higher cognitive and lung functioning groups had better INCATM adherence. Attempted and Attempted Interval predicted health status, while Doses Used Rate predicted quality-of-life.

Conclusion: INCATM did not strongly correlate with self-report or prescription refill data. Discriminant and predictive validity demonstrated by INCATM suggests the potential utility of the INCATM as a method to identify intentional and unintentional adherence to inhaled medication and facilitate targeted intervention.

Funding

Royal College of Surgeons in Ireland Research Institute, grant number 1855

History

Comments

This is an Accepted Manuscript of an article published by Taylor & Francis in Psychology & Health on 2017, available online: http://www.tandfonline.com/ http://dx.doi.org/10.1080/08870446.2017.1290243

Published Citation

Moran C, Doyle F, Sulaiman I, Bennett K, Green G, Molloy GJ, Reilly RB, Costello RW, Mellon L. The INCATM (Inhaler Compliance AssessmentTM): A comparison with established measures of adherence. Psychology & Health. 2017;28:1-21

Publication Date

01/02/2017

Publisher

Taylor & Francis Group

PubMed ID

28276739

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