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A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity.

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journal contribution
posted on 13.10.2021, 09:33 by Darren GriffithDarren Griffith, Maria MorganMaria Morgan, Celine MarmionCeline Marmion

The successful design and synthesis of a novel multifunctional platinum drug candidate with DNA binding, histone deacetylase inhibitory activity and enhanced selectivity for cancer cells are described.

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Published Citation

Griffith D, Morgan MP, Marmion CJ. A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity. Chem Commun (Camb). 2009;44:6735-6737

Publication Date

2009-11-28

PubMed ID

19885462

Department/Unit

  • Chemistry
  • School of Pharmacy and Biomolecular Sciences