A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity.

Griffith, Darren; Morgan, Maria; Marmion, Celine

A novel anti-cancer bifunctional platinum drug candidate with dua.pdf (535.98 kB)

A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity.

journal contribution

posted on 2021-10-13, 09:33 authored by Darren GriffithDarren Griffith, Maria MorganMaria Morgan, Celine MarmionCeline Marmion

The successful design and synthesis of a novel multifunctional platinum drug candidate with DNA binding, histone deacetylase inhibitory activity and enhanced selectivity for cancer cells are described.

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Published Citation

Griffith D, Morgan MP, Marmion CJ. A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity. Chem Commun (Camb). 2009;44:6735-6737