Apolipoprotein A I enhances activated protein C cytoprotective activity.pdf (855.96 kB)
Download fileApolipoprotein A-I enhances activated protein C cytoprotective activity
journal contribution
posted on 2021-04-30, 14:01 authored by Eimear M Gleeson, Aisling Rehill, Orla Willis Fox, Fionnuala Ni Ainle, Cormac McDonnell, Hannah Rushe, Sean McCluskey, James O'DonnellJames O'Donnell, Roger PrestonRoger PrestonHigh-density lipoprotein and apolipoprotein A-I enhance activated protein C cytoprotective activity.
High-density lipoprotein and apolipoprotein A-I significantly increase the rate at which activated protein C degrades cytotoxic extracellular histones.
Funding
Science Foundation Ireland Career Development Award (15/CDA/3499)
Technology and Innovation Development Award (18/TIDA/6001)
National Children’s Research Centre Project Award (C/18/3)
History
Comments
This research was originally published in Blood Advances. Gleeson EM, Rehill AM, Willis Fox O, Ni Ainle F, McDonnell CJ, Rushe HJ, McCluskey S, O'Donnell JS, Preston RJS. Apolipoprotein A-I enhances activated protein C cytoprotective activity. Blood Advances. 2020;4(11):2404-2408. © the American Society of Hematology.Published Citation
Gleeson EM, Rehill AM, Willis Fox O, Ni Ainle F, McDonnell CJ, Rushe HJ, McCluskey S, O'Donnell JS, Preston RJS. Apolipoprotein A-I enhances activated protein C cytoprotective activity. Blood Advances. 2020;4(11):2404-2408.Publication Date
2 June 2020External DOI
PubMed ID
32484855Department/Unit
- Irish Centre for Vascular Biology
- School of Pharmacy and Biomolecular Sciences
Research Area
- Health Professions Education
- Vascular Biology
Publisher
American Society of HematologyVersion
- Published Version (Version of Record)
