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Association of neighbourhood-level material deprivation with adverse outcomes and processes of care among patients with heart failure in a single-payer healthcare system: a population-based cohort study

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posted on 2024-02-13, 16:54 authored by David Bobrowski, Andrew Dorovenis, Husam Abdel-Qadir, Candace D McNaughton, Rea Alonzo, Jiming Fang, Peter C Austin, Jacob A Udell, Cynthia A Jackevicius, David A Alter, Clare L Atzema, R Sacha Bhatia, Gillian L Booth, Andrew C T Ha, Sharon Johnston, Irfan Dhalla, Moira K Kapral, Harlan M Krumholz, Idan Roifman, Harindra C Wijeysundera, Dennis T Ko, Karen Tu, Heather J Ross, Michael J Schull, Douglas S Lee

Aim: We studied the association between neighbourhood material deprivation, a metric estimating inability to attain basic material needs, with outcomes and processes of care among incident heart failure patients in a universal healthcare system.

Methods and results: In a population-based retrospective study (2007-2019), we examined the association of material deprivation with 1-year all-cause mortality, cause-specific hospitalization, and 90-day processes of care. Using cause-specific hazards regression, we quantified the relative rate of events after multiple covariate adjustment, stratifying by age ≤65 or ≥66 years. Among 395 763 patients (median age 76 [interquartile range 66-84] years, 47% women), there was significant interaction between age and deprivation quintile for mortality/hospitalization outcomes (p ≤ 0.001). Younger residents (age ≤65 years) of the most versus least deprived neighbourhoods had higher hazards of all-cause death (hazard ratio [HR] 1.19, 95% confidence interval [CI] 1.10-1.29]) and cardiovascular hospitalization (HR 1.29 [95% CI 1.19-1.39]). Older individuals (≥66 years) in the most deprived neighbourhoods had significantly higher hazard of death (HR 1.11 [95% CI 1.08-1.14]) and cardiovascular hospitalization (HR 1.13 [95% CI 1.09-1.18]) compared to the least deprived. The magnitude of the association between deprivation and outcomes was amplified in the younger compared to the older age group. More deprived individuals in both age groups had a lower hazard of cardiology visits and advanced cardiac imaging (all p < 0.001), while the most deprived of younger ages were less likely to undergo implantable cardioverter-defibrillator/cardiac resynchronization therapy-pacemaker implantation (p = 0.023), compared to the least deprived.

Conclusion: Patients with newly-diagnosed heart failure residing in the most deprived neighbourhoods had worse outcomes and reduced access to care than those less deprived.

Funding

Canadian Institutes of Health Research (grant # FDN143313 and grant # FDN148446)

History

Comments

The original article is available at https://onlinelibrary.wiley.com/

Published Citation

Bobrowski D, et al. Association of neighbourhood-level material deprivation with adverse outcomes and processes of care among patients with heart failure in a single-payer healthcare system: a population-based cohort study. Eur J Heart Fail. 2023;25(12):2274-2286.

Publication Date

13 November 2023

PubMed ID

37953731

Department/Unit

  • Undergraduate Research

Publisher

John Wiley & Sons, Inc

Version

  • Published Version (Version of Record)