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BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential.

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journal contribution
posted on 14.03.2022, 11:42 authored by Harrison C. Daly, Gonzalo Sampedro, Corentin Bon, Dan WuDan Wu, Ghazi Ismail, Ronan A. Cahill, Donal O'SheaDonal O'Shea

The use of near-infrared fluorescence for in vivo research and intraoperative clinical imaging is rapidly expanding, with new applications being proposed and developed. While imaging hardware and software have significantly progressed in recent times, the molecular fluorescent agents remain a limiting factor. In this report, the design, synthesis, photophysical characterization and bio-medical imaging assessment of two new NIR-fluorophores based on the BF

Funding

Science Foundation Ireland grant number 11/PI/1071(T).

History

Comments

The original article is available at www.sciencedirect.com

Published Citation

Daly HC, Sampedro G, Bon C, Wu D, Ismail G, Cahill RA, O'Shea DF. BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential. European Journal of Medicinal Chemistry. 2017;135:392-400

Publication Date

2017-07-28

PubMed ID

28460313

Department/Unit

  • Chemistry