BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential.
The use of near-infrared fluorescence for in vivo research and intraoperative clinical imaging is rapidly expanding, with new applications being proposed and developed. While imaging hardware and software have significantly progressed in recent times, the molecular fluorescent agents remain a limiting factor. In this report, the design, synthesis, photophysical characterization and bio-medical imaging assessment of two new NIR-fluorophores based on the BF
Science Foundation Ireland grant number 11/PI/1071(T).
CommentsThe original article is available at www.sciencedirect.com
Published CitationDaly HC, Sampedro G, Bon C, Wu D, Ismail G, Cahill RA, O'Shea DF. BF2-azadipyrromethene NIR-emissive fluorophores with research and clinical potential. European Journal of Medicinal Chemistry. 2017;135:392-400