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Benign gynaecological pathology causing vascular presentations: three cases of women with peripheral thromboses

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posted on 2024-04-15, 15:58 authored by Amy P Worrall, M J Connolly, C Kelly, N O'Connor-Byrne, A Keeling, Siobhan GlaveySiobhan Glavey, H Rajab, P Naughton

Introduction 

Benign or malignant gynaecological disease can compress iliac vessels leading to deep vein thrombosis (DVT) or acute arterial ischemia. Women have a higher incidence of thrombosis in comparison to males, with a higher prevalence of pro-thrombotic factors such as pregnancy, use of combined oral contraceptives, and gynaecological pathologies. 

Cases 

Case 1 is a 45-year old Caucasian woman who presented with a left sided DVT, menorrhagia and anaemia secondary to a multi-fibroid uterus. Case 2 was a 38 year old Caucasian female who presented with a left sided DVT secondary to a singular large uterine fibroid (21cm diameter). Case 3 was a Caucasian female who presented with acute arterial ischemia and contralateral DVT due to compressive effect from a exceptionally large benign ovarian pathology. 

Results 

This case series highlights the need to consider vascular complications in young female patients as sequelae of possible pelvic pathology. 

Conclusion 

Investigation for pelvic gynaecological disease should be considered in assessment of women with lower limb thrombotic vascular pathology, especially in the absence of typical vascular risk factors 

History

Comments

The original article is available at www.imj.ie

Published Citation

Worrall AP. et al. Benign gynaecological pathology causing vascular presentations: three cases of women with peripheral thromboses. Ir Med J. 2024;117(1):891.

Publication Date

18 January 2024

PubMed ID

38259222

Department/Unit

  • Beaumont Hospital
  • Pathology

Publisher

Irish Medical Association

Version

  • Published Version (Version of Record)