Royal College of Surgeons in Ireland
COVID-19-induced takotsubo cardiomyopathy.pdf (1.63 MB)

COVID-19-induced takotsubo cardiomyopathy: Venturing beyond the obvious

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journal contribution
posted on 2021-05-06, 10:44 authored by Talal Almas, Tarek Khedro, Abdul Haadi, Reema Ahmed, Lamees Alshaikh, Abdulla Hussain Al-Awaid, Muhammad Siyab Panhwar, Hafeez Ul Hassan Virk

Takotsubo cardiomyopathy (TCM), colloquially known as “broken heart syndrome,” is a relatively uncommon transient condition that is characterized by left ventricular apical ballooning [1]. It is purported to be triggered by exorbitant physical or emotional stressors. The clinical picture elicited by TCM closely mimics that of acute coronary syndrome (ACS), with most patients presenting with substernal chest pain and ECG changes akin to those observed in a patient with acute myocardial infarction [1]. Interestingly, in cases of TCM, coronary arteries are noted to be unremarkable upon catheterization [1,2]. Due to the remarkably similar clinical semblance elicited by TCM and myocardial infarction, it remains critically imperative to distinguish between the two pathologies. Of note, TCM remains a diagnosis of exclusion, and ischemic cardiomyopathy must be excluded prior to its diagnosis. The diagnosis of TCM is rendered in accordance with the criteria outlined by Mayo Clinic [3]. This is delineated by Fig. 1.



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Published Citation

Almas T, Khedro T, Haadi A, Ahmed R, Alshaikh L, Al-Awaid AH, Panhwar MS, Virk HUH. COVID-19-induced takotsubo cardiomyopathy: Venturing beyond the obvious. Annals of Medicine and Surgery. 2021;65:102291

Publication Date

15 April 2021

PubMed ID



  • RCSI Bahrain
  • Undergraduate Research




  • Published Version (Version of Record)