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COVID-19, hypercoagulation and what it could mean for patients with psychotic disorders

journal contribution
posted on 2022-09-02, 12:50 authored by David MonganDavid Mongan, Mary CannonMary Cannon, David CotterDavid Cotter

It has been recently shown that COVID-19 is associated with a clinically significant coagulopathy. Several studies have indicated that elevated markers of fibrin degradation (D-dimers) in hospitalised patients are associated with poorer prognosis (death or ICU admission) (Fogarty et al., 2020, Connors and Levy, 2020). Coagulation test screening is suggested and routine thromboprophylaxis measures (including use of low molecular weight heparin) are recommended, although full anticoagulation is not yet advised in the management of such patients unless otherwise clinically indicated (Connors and Levy, 2020). We wish to draw attention to a potentially enhanced risk of thromboembolic complications in patients with psychotic disorders. 

Funding

Irish Clinical Academic Training (ICAT) Programme

Wellcome Trust and the Health Research Board (Grant Number 203930/B/16/Z)

Health Service Executive National Doctors Training and Planning and the Health and Social Care, Research and Development Division, Northern Ireland

European Research Council Consolidator Award (iHEAR 724809)

History

Comments

The original article is available at https://www.sciencedirect.com/

Published Citation

Mongan D, Cannon M, Cotter DR. COVID-19, hypercoagulation and what it could mean for patients with psychotic disorders. Brain Behav Immun. 2020;88:9-10.

Publication Date

29 May 2020

PubMed ID

32473945

Department/Unit

  • Psychiatry

Research Area

  • Neurological and Psychiatric Disorders
  • Immunity, Infection and Inflammation

Publisher

Elsevier BV

Version

  • Accepted Version (Postprint)