DNA Microarray Genotyping and Virulence and Antimicrobial Resistance Gene Profiling of Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates from Renal Patients.

McNicholas, Sinead; Shore, Anna C.; Coleman, David C.; Humphreys, Hilary; Fitzgerald Hughes, Deirdre

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DNA Microarray Genotyping and Virulence and Antimicrobial Resistance Gene Profiling of Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates from Renal Patients.

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posted on 2022-04-01, 11:40 authored by Sinead McNicholas, Anna C. Shore, David C. Coleman, Hilary HumphreysHilary Humphreys, Deirdre Fitzgerald HughesDeirdre Fitzgerald Hughes

Thirty-six methicillin-resistant Staphylococcus aureus (MRSA) bloodstream isolates from renal patients were genetically characterized by DNA microarray analysis and spa typing. The isolates were highly clonal, belonging mainly to ST22-MRSA-IV. The immune evasion and enterotoxin gene clusters were found in 29/36 (80%) and 33/36 (92%) of isolates, respectively.

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McNicholas S, Shore AC, Coleman DC, Humphreys H, Fitzgerald Hughes D. DNA Microarray Genotyping and Virulence and Antimicrobial Resistance Gene Profiling of Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates from Renal Patients. J Clin Microbiol. 2011 Sep 21. [Epub ahead of print]