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Daily physical activity patterns and their associations with cardiometabolic biomarkers: The Maastricht Study

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posted on 2024-01-04, 11:10 authored by Tuija Leskinen, Valeria Lima PassosValeria Lima Passos, Pieter C Dagnelie, Hans H C M Savelberg, Bastiaan E DE Galan, Simone J P M Eussen, Coen D A Stehouwer, Sari Stenholm, Annemarie Koster

Purpose: This study aimed to identify physical activity patterns and examine their association with cardiometabolic biomarkers in a cross-sectional design.

Methods: Overall 6072 participants (mean age, 60.2 yr; SD 8.6 yr, 50% women) from The Maastricht Study provided daily physical activity data collected with thigh-worn activPAL3 accelerometers. The patterns of daily physical activity over weekdays and weekend days were identified by using Group Based Trajectory Modeling. Cardiometabolic biomarkers included body mass index, waist circumference, office blood pressure, glucose, HbA1c, and cholesterol levels. Associations between the physical activity patterns and cardiometabolic outcomes were examined using the analyses of covariance adjusted for sex, age, education, smoking, and diet. Because of statistically significant interaction, the analyses were stratified by type 2 diabetes status.

Results: Overall, seven physical activity patterns were identified: consistently inactive (21% of participants), consistently low active (41%), active on weekdays (15%), early birds (2%), consistently moderately active (7%), weekend warriors (8%), and consistently highly active (6%). The consistently inactive and low active patterns had higher body mass index, waist, and glucose levels compared with the consistently moderately and highly active patterns, and these associations were more pronounced for participants with type 2 diabetes. The more irregular patterns accumulated moderate daily total activity levels but had rather similar cardiometabolic profiles compared with the consistently active groups.

Conclusions: The cardiometabolic profile was most favorable in the consistently highly active group. All patterns accumulating moderate to high levels of daily total physical activity had similar health profile suggesting that the amount of daily physical activity rather than the pattern is more important for cardiometabolic health.

Funding

European Regional Development Fund via OP-Zuid, the Province of Limburg

Dutch Ministry of Economic Affairs (grant 31O.041)

Stichting De Weijerhorst (Maastricht, The Netherlands)

Pearl String Initiative Diabetes (Amsterdam, the Netherlands)

Cardiovascular Center (CVC, Maastricht, The Netherlands)

CARIM School for Cardiovascular Diseases (Maastricht, The Netherlands)

CAPHRI Care and Public Health Research Institute (Maastricht, The Netherlands)

NUTRIM School for Nutrition and Translational Research in Metabolism (Maastricht, The Netherlands)

Stichting Annadal (Maastricht, the Netherlands)

Health Foundation Limburg (Maastricht, The Netherlands)

Janssen-Cilag B. V. (Tilburg, The Netherlands)

Novo Nordisk Farma B. V. (Alphen aan den Rijn, The Netherlands)

Sanofi-Aventis Netherlands B. V. (Gouda, The Netherlands)

Academy of Finland (grant 332030)

History

Comments

The original article is available at https://journals.lww.com/

Published Citation

Leskinen T. et al. Daily physical activity patterns and their associations with cardiometabolic biomarkers: The Maastricht Study. Med Sci Sports Exerc. 2023;55(5):837-846

Publication Date

1 May 2023

PubMed ID

36728772

Department/Unit

  • School of Pharmacy and Biomolecular Sciences

Publisher

Lippincott Williams & Wilkins

Version

  • Published Version (Version of Record)