Royal College of Surgeons in Ireland
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Diuretic therapy in congestive heart failure.

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journal contribution
posted on 2021-03-24, 14:37 authored by Patrick Kennelly, Rajju Sapkota, Maimoona Azhar, Faisal Habib Cheema, Claire ConwayClaire Conway, Aamir HameedAamir Hameed
In heart failure, fluid overload is a major pathological mechanism leading to vascular congestion, pulmonary congestion and elevated jugular venous pressures. Diuretics play a significant role in the management of patients with congestive heart failure. It is used to relieve the congestive symptoms of heart failure. However, the appropriate use of diuretics remains challenging due to various complications like electrolyte abnormalities, worsening renal function and diuretic resistance. This has prompted towards the search of safer and effective alternatives. This review evaluates the use of diuretics in congestive heart failure and discusses the complications of different types of diuretics, which is essential for successful management of congestion in patients with heart failure and hence to optimise the outcome for the patients.



This is an Accepted Manuscript of an article published by Taylor & Francis in Acta Cardiologica in 2021 available online: DOI:

Published Citation

Kennelly P, Sapkota R, Azhar M, Cheema FH, Conway C, Hameed A. Diuretic therapy in congestive heart failure. Acta Cardiologica. 2021:1-8.

Publication Date

3 Mar 2021

PubMed ID



  • Anatomy and Regenerative Medicine
  • RCSI Tissue Engineering Group (TERG)
  • Undergraduate Research
  • School of Medicine

Research Area

  • Surgical Science and Practice
  • Biomaterials and Regenerative Medicine


Informa UK Limited


  • Accepted Version (Postprint)