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Existing validated clinical prediction rules for predicting response to physiotherapy interventions for musculoskeletal conditions have limited clinical value: a systematic review

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journal contribution
posted on 03.05.2022, 10:57 by Mary E Walsh, Helen FrenchHelen French, Emma Wallace, Sarah Madden, Patricia King, Tom FaheyTom Fahey, Rose GalvinRose Galvin
Objective: To systematically review clinical prediction rules (CPRs) that have undergone validation testing for predicting response to physiotherapy-related interventions for musculoskeletal conditions.
Study design and setting: PubMed, EMBASE, CINAHL and Cochrane Library were systematically searched to September 2020. Search terms included musculoskeletal (MSK) conditions, physiotherapy interventions and clinical prediction rules. Controlled studies that validated a prescriptive CPR for physiotherapy treatment response in musculoskeletal conditions were included. Two independent reviewers assessed eligibility. Original derivation studies of each CPR were identified. Risk of bias was assessed with the PROBAST tool (derivation studies) and the Cochrane Effective Practice and Organisation of Care group criteria (validation studies).
Results: Nine studies aimed to validate seven prescriptive CPRs for treatment response for MSK conditions including back pain, neck pain, shoulder pain and carpal tunnel syndrome. Treatments included manipulation, traction and exercise. Seven studies failed to demonstrate an association between CPR prediction and outcome. Methodological quality of derivation studies was poor and for validation studies was good overall.
Conclusion: Results do not support the use of any CPRs identified to aid physiotherapy treatment selection for common musculoskeletal conditions, due to methodological shortcomings in the derivation studies and lack of association between CPR and outcome in validation studies.

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Comments

The original article is available at https://www.sciencedirect.com/

Published Citation

Walsh ME, et al. Existing validated clinical prediction rules for predicting response to physiotherapy interventions for musculoskeletal conditions have limited clinical value: a systematic review. J Clin Epidemiol. 2021;135:90-102.

Publication Date

9 February 2021

PubMed ID

33577988

Department/Unit

  • HRB Centre for Primary Care Research
  • General Practice
  • School of Physiotherapy

Research Area

  • Population Health and Health Services

Publisher

Elsevier BV

Version

  • Published Version (Version of Record)