Royal College of Surgeons in Ireland
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From early birds to night owls: a review of chronobiology

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journal contribution
posted on 2023-08-21, 11:13 authored by Christine Okeefe

The field of chronobiology can be used to better understand variations in human health. First described in the 1700s, it seeks to explore the mechanisms underlying the various body rhythms in humans and the consequences of altering these rhythms in terms of pathology. Several key genes have been discovered and various tools have been created to determine an individual’s particular chronotype. Studies have demonstrated that variations in rhythms are potentially implicated in the development of various gastrointestinal, cardiovascular, neurological, and infectious disease processes. Finally, tailoring treatment to a person’s circadian rhythm, termed chronotherapeutics, appears to have a benefit in reducing morbidity from disease. This review seeks to provide an overview of this exciting field. 



The original article is available at Part of the RCSIsmj collection:

Published Citation

Okeefe C. From early birds to night owls: a review of chronobiology. RCSIsmj. 2021;14(1):61-68

Publication Date



  • Undergraduate Research


RCSI University of Medicine and Health Sciences


  • Published Version (Version of Record)