Royal College of Surgeons in Ireland
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Genomic evidence of SARS-CoV-2 reinfection in Ireland

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posted on 2022-10-24, 13:33 authored by Sinead O'DonnellSinead O'Donnell, J Dean, G Gonzalez, Carr M, J Cafferkey, A Ni Dhuthaigh, Eoghan De BarraEoghan De Barra, C De Gascun, K Burns, K O’Connell, Fidelma FitzpatrickFidelma Fitzpatrick

Presentation 

A 40-year-old healthcare worker (HCW) presented with cough, headache, sore throat, fatigue and myalgia seven months after primary infection with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms were milder and recovery was faster on the second episode. 

Diagnosis 

Reinfection with phylogenetically distinct SARS-CoV-2 was confirmed by whole-genome sequencing (WGS). 

Treatment 

Management involved symptomatic treatment and self-isolation. 

Discussion 

The incidence of SARS-CoV-2 reinfection is not well characterised. Infection control precautions may still be required in healthcare facilities, even in previously infected and possibly in vaccinated individuals while SARS-CoV-2 remains in circulation. Further research on the nature and duration of immunity is required to inform public health and infection control policy.

History

Comments

The original article is available at www.imj.ie

Published Citation

O’Donnell S. et al. Genomic evidence of SARS-CoV-2 reinfection in Ireland. Ir Med J. 2021;114(5):365

Publication Date

May 2021

Department/Unit

  • Beaumont Hospital
  • Clinical Microbiology
  • International Health and Tropical Medicine

Publisher

Irish Medical Association

Version

  • Published Version (Version of Record)