Genomic evidence of SARS-CoV-2 reinfection in Ireland
Presentation
A 40-year-old healthcare worker (HCW) presented with cough, headache, sore throat, fatigue and myalgia seven months after primary infection with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms were milder and recovery was faster on the second episode.
Diagnosis
Reinfection with phylogenetically distinct SARS-CoV-2 was confirmed by whole-genome sequencing (WGS).
Treatment
Management involved symptomatic treatment and self-isolation.
Discussion
The incidence of SARS-CoV-2 reinfection is not well characterised. Infection control precautions may still be required in healthcare facilities, even in previously infected and possibly in vaccinated individuals while SARS-CoV-2 remains in circulation. Further research on the nature and duration of immunity is required to inform public health and infection control policy.
History
Comments
The original article is available at www.imj.iePublished Citation
O’Donnell S. et al. Genomic evidence of SARS-CoV-2 reinfection in Ireland. Ir Med J. 2021;114(5):365Publication Date
May 2021Department/Unit
- Beaumont Hospital
- Clinical Microbiology
- International Health and Tropical Medicine
Publisher
Irish Medical AssociationVersion
- Published Version (Version of Record)