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Guillain-Barré syndrome is immunogenic in SARS-CoV-2 infected.

journal contribution
posted on 09.02.2022, 10:13 authored by Josef Finsterer, Talal Almas
With interest, we read the article by Khan et al. about five adult patients with SARS-CoV-2 associated Guillain-Barré syndrome (SACAG) of whom one tested positive for virus RNA in the cerebrospinal fluid (CSF). Three patients were classified as acute, inflammatory, demyelinating polyneuropathy (AIDP) and one each as acute, motor, axonal neuropathy (AMAN) respectively acute, motor, and sensory, axonal neuropathy (AMSAN). It was concluded that “in a few cases where the symptoms of COVID-19 and GBS occur concurrently (corresponding to the viremic phase), a separate, para-infectious pathogenesis needs to be thought of”. The study is appealing but prompts comments and concerns.

History

Comments

This is the peer reviewed version of the following article: Finsterer J, Almas T. Guillain-Barré syndrome is immunogenic in SARS-CoV-2 infected. J Med Virol. 2022 ;94(1):22-23, which has been published in final form at https://doi.org/10.1002/jmv.27314 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

Published Citation

Finsterer J, Almas T. Guillain-Barré syndrome is immunogenic in SARS-CoV-2 infected. J Med Virol. 2022 ;94(1):22-23

Publication Date

1 September 2021

PubMed ID

34468997

Department/Unit

  • Undergraduate Research

Publisher

Wiley

Version

  • Accepted Version (Postprint)