Integrins as therapeutic targets for SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus of the genus Betacoronavirus. Its genome is composed of four structural proteins known as spike (S), envelope (E), membrane (M), and nucleocapsid (N), of which E, M, and N are integrated into the viral envelope. The S glycoprotein, which protrudes from the surface of mature virions as a spike, is essential for virus attachment, fusion, and entry into the host cell.
CommentsThe original article is available at https://www.frontiersin.org/
Published CitationGressett TE, Nader D, Robles JP, Buranda T, Kerrigan SW, Bix G. Integrins as therapeutic targets for SARS-CoV-2. Front Cell Infect Microbiol. 2022;12:892323.
Publication Date29 April 2022
- School of Pharmacy and Biomolecular Sciences
PublisherFrontiers Media S.A.
- Published Version (Version of Record)