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Invasive pneumococcal surveillance to assess the potential benefits of extended spectrum conjugate vaccines (PCV15/PCV20) in older adults

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posted on 2023-02-28, 17:26 authored by Hilary HumphreysHilary Humphreys, Mary CorcoranMary Corcoran, Jolita Mereckiene, Robert CunneyRobert Cunney, Suzanne Cotter

The introduction of pneumococcal conjugate vaccines (PCV) into the childhood vaccination programme has reduced invasive pneumococcal disease (IPD). Although anticipated from data elsewhere, surveillance in Ireland has confirmed reductions in IPD amongst those ≥65 years of age due to a decline of PCV serotypes in this age group. Currently, direct protection against IPD in the elderly is focused on immunisation with the 23-valent pneumococcal polysaccharide vaccine (PPV23). However, immunity may not be as effective as with PCV and, furthermore, PPV23 uptake is poor in Ireland. Hence, consideration should be given to providing a PCV to this age group. Word count= 98 (limit, 100)

Funding

Health Protection Surveillance Centre (Ireland)

Pfizer Healthcare (Ireland)

ECDC (SpIDnet project)

European Commission (Horizon 2020)

History

Comments

The original article is available at https://www.cambridge.org/

Published Citation

Humphreys H, Corcoran M, Mereckiene J, Cunney R, Cotter S. Invasive pneumococcal surveillance to assess the potential benefits of extended spectrum conjugate vaccines (PCV15/PCV20) in older adults. Epidemiol Infect. 2023;151:e27

Publication Date

26 January 2023

PubMed ID

36700424

Department/Unit

  • Beaumont Hospital
  • Clinical Microbiology

Publisher

Cambridge University Press

Version

  • Published Version (Version of Record)