Molecular Characterization of Nasal Methicillin-Resistant Staphyl.pdf (204.79 kB)
Molecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization.
journal contribution
posted on 2022-03-01, 12:35 authored by Toney PoovelikunnelToney Poovelikunnel, Paulo E. Budri, Anna C. Shore, David C. Coleman, Hilary HumphreysHilary Humphreys, Deirdre Fitzgerald HughesDeirdre Fitzgerald HughesSequential methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients following attempted mupirocin nasal decolonization showed an increase in mupirocin resistance (MR) from 6.6% to 20%. MR isolates from patients who failed decolonization yielded indistinguishable spa types and carried multiple antimicrobial and antiseptic resistance genes, which may guide infection control and prevention.
Funding
Health Research Board Ireland (HPF/2013-495). Pfizer and Astellas.
History
Comments
The original article is available at https://aac.asm.orgPublished Citation
Poovelikunnel TT, Budri PE, Shore AC, Coleman DC, Humphreys H, Fitzgerald-Hughes D. Molecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization. Antimicrobial Agents and Chemotherapy. 2018;62(9):pii: e00819-18.Publication Date
2018-08-27External DOI
PubMed ID
29914942Department/Unit
- Beaumont Hospital
- Clinical Microbiology
