Nano-clays as Potential Pseudo-antibodies for COVID-19.pdf (3.82 MB)
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Nano-clays as potential pseudo-antibodies for COVID-19

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journal contribution
posted on 07.02.2022, 14:10 authored by Sahel N Abduljauwad, Taimur Habib, Habib-ur-Rehman Ahmed
Despite several efforts, the development of an effective vaccine for COVID-19 may take a much longer time. Traditional/natural medicine, already experienced by humans, could be an earlier solution. Considering the research team's experience in using nano-clays as high-affinity material for cancer metastasis, melanoma treatment, and bone regeneration, we propose to use these nano-clays for the prevention/treatment of COVID-19. Owing to high affinity, nano-clays would capture the viruses before the latter get engaged with human hACE2. In this study, molecular-level simulations and modeling of the interaction of coronavirus spike and hACE2 proteins were performed with and without nano-clays. The results showed a very high level of affinity/cohesiveness among SARS-CoV-2 spike and nano-clays as compared to the one between the former and hACE2. We premise that these nano-clays since already being used as drug carriers could also be injected as "clays-alone" medicine. Recommendations have also been provided for future in vitro and in vivo studies.

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The original article is available at https://nanoscalereslett.springeropen.com/

Published Citation

Abduljauwad SN, Habib T, Ahmed HU. Nano-clays as potential pseudo-antibodies for COVID-19. Nanoscale Res Lett. 2020;15(1):173

Publication Date

28 August 2020

PubMed ID

32857226

Department/Unit

  • RCSI Bahrain

Publisher

Springer

Version

  • Published Version (Version of Record)