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Nanotechnology in pulmonary medicine

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journal contribution
posted on 18.05.2022, 14:32 authored by Mohammad Doroudian, Andrew O’ Neill, Ronan MacLoughlinRonan MacLoughlin, Adriele Prina Mello, Yuri Volkov, Seamas C. Donnelly
Nanotechnology in medicine—nanomedicine—is extensively employed to diagnose, treat, and prevent pulmonary diseases. Over the last few years, this brave new world has made remarkable progress, offering opportunities to address historical clinical challenges in pulmonary diseases including multidrug resistance, adverse side effects of conventional therapeutic agents, novel imaging, and earlier disease detection. Nanomedicine is also being applied to tackle the new emerging infectious diseases, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), influenza A virus subtype H1N1 (A/H1N1), and more recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this review we provide both a historical overview of the application of nanomedicine to respiratory diseases and more recent cutting-edge approaches such as nanoparticle-mediated combination therapies, novel double-targeted nondrug delivery system for targeting, stimuli-responsive nanoparticles, and theranostic imaging in the diagnosis and treatment of pulmonary diseases.

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The original article is available at https://www.sciencedirect.com/

Published Citation

Doroudian M, O' Neill A, Mac Loughlin R, Prina-Mello A, Volkov Y, Donnelly SC. Nanotechnology in pulmonary medicine. Curr Opin Pharmacol. 2020;56:85-92.

Publication Date

17 December 2020

PubMed ID

33341460

Department/Unit

  • School of Pharmacy and Biomolecular Sciences

Publisher

Elsevier B.V.

Version

  • Published Version (Version of Record)