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Nicotine e-vaping and cardiovascular consequences: a case series and literature review

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posted on 18.05.2022, 15:27 authored by Maryam Jessri, Ahmed S Sultan, Emad Magdy, Niamh Hynes, Sherif Sultan
Background: Cardiovascular toxicity as a consequence of nicotine from conventional tobacco cigarette smoking is well documented. However, little is known about the cardiovascular consequences of nicotine e-vaping. We review the literature and report a case series of three cases of major adverse cardiovascular clinical effects post nicotine e-vaping.
Case summary: Three patients with known peripheral arterial disease who switched from heavy cigarette smoking consumption to a high-intensity dose of nicotine e-vaping all developed further arterial complications within 6-30 months.
Discussion: With the recent epidemic of e-vaping in young individuals and the national outbreak of e-vaping use-associated lung injury (EVALI), the dangers of e-vaping are now coming to light. The pulmonary effects are now well described, and this paper highlights three new cases of cardiovascular toxicity associated with e-vaping. The potential role of nicotine e-vaping and the risk of coronavirus disease-2019 (COVID-19) will also be discussed.



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Published Citation

Jessri M, Sultan AS, Magdy E, Hynes N, Sultan S. Nicotine e-vaping and cardiovascular consequences: a case series and literature review. Eur Heart J Case Rep. 2020;4(6):1-7.

Publication Date

12 November 2020

PubMed ID



  • School of Medicine


Oxford University Press


  • Published Version (Version of Record)