Optimising the method for isolating ocular surface microRNA using impression cytology.pdf (322.63 kB)
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Optimising the method for isolating ocular surface microRNA using impression cytology

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Conjunctival impression cytology (CIC) has evolved as a reliable method for obtaining superficial epithelial cells from the ocular surface in comparison to more invasive harvesting techniques such as brush cytology, smears and biopsies. Its use in research has played a critical role in adding to our understanding of ocular surface pathology and as its molecular applications broaden, it may facilitate the development of targeted therapies and personalised medicine in the future 

Funding

Utilising microRNA-based therapeutics for the development of novel targeted drug delivery device for patients with dry eye disease (DED) | Funder: Royal Victoria Eye & Ear Hospital Research Foundation | Grant ID: RVEEH-RCSI-2019

Utilising microRNA-based therapeutics for the development of novel targeted drug delivery device for patients with dry eye disease (DED) | Funder: Irish College of Opthalmologists - ICO | Grant ID: N/A

Funding for PhD Project | Funder: RCSI | Grant ID: RCSI-VISICORT

History

Comments

The original article is available at https://www.sciencedirect.com/

Published Citation

Greenan E, Murphy CC, Ní Gabhann-Dromgoole J. Optimising the method for isolating ocular surface microRNA using impression cytology. Ocul Surf. 2021;22:83-85

Publication Date

31 July 2021

PubMed ID

34343715

Department/Unit

  • Ophthalmology
  • School of Pharmacy and Biomolecular Sciences

Research Area

  • Chemistry and Pharmaceutical Sciences
  • Health Professions Education
  • Surgical Science and Practice
  • Biomaterials and Regenerative Medicine
  • Immunity, Infection and Inflammation

Publisher

Elsevier BV

Version

  • Published Version (Version of Record)