Royal College of Surgeons in Ireland
Browse

Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life.

Download (1.04 MB)
journal contribution
posted on 2024-10-18, 15:50 authored by Lisa S van Tol, Miriam L Haaksma, Matteo Cesari, Frances DockeryFrances Dockery, Irma H J Everink, Bahaa N Francis, Adam L Gordon, Stefan Grund, Luba Matchekhina, Laura Monica Perez Bazan, Jos M G A Schols, Eva Topinková, Mark A Vassallo, Monique A A Caljouw, Wilco P Achterberg, EU-COGER consortium

Background: After an acute infection, older persons may benefit from geriatric rehabilitation (GR).

Objectives: This study describes the recovery trajectories of post-COVID-19 patients undergoing GR and explores whether frailty is associated with recovery.

Design: Multicentre prospective cohort study.

Setting: 59 GR facilities in 10 European countries.

Participants: Post-COVID-19 patients admitted to GR between October 2020 and October 2021.

Methods: Patients' characteristics, daily functioning (Barthel index; BI), quality of life (QoL; EQ-5D-5L) and frailty (Clinical Frailty Scale; CFS) were collected at admission, discharge, 6 weeks and 6 months after discharge. We used linear mixed models to examine the trajectories of daily functioning and QoL.

Results: 723 participants were included with a mean age of 75 (SD: 9.91) years. Most participants were pre-frail to frail (median [interquartile range] CFS 6.0 [5.0-7.0]) at admission. After admission, the BI first steeply increased from 11.31 with 2.51 (SE 0.15, P < 0.001) points per month and stabilised around 17.0 (quadratic slope: -0.26, SE 0.02, P < 0.001). Similarly, EQ-5D-5L first steeply increased from 0.569 with 0.126 points per month (SE 0.008, P < 0.001) and stabilised around 0.8 (quadratic slope: -0.014, SE 0.001, P < 0.001). Functional recovery rates were independent of frailty level at admission. QoL was lower at admission for frailer participants, but increased faster, stabilising at almost equal QoL values for frail, pre-frail and fit patients.

Conclusions: Post-COVID-19 patients admitted to GR showed substantial recovery in daily functioning and QoL. Frailty at GR admission was not associated with recovery and should not be a reason to exclude patients from GR.

Funding

Leiden University Fund (Leiden Empowerment Fund, grant number LEF2106-2-47)

Zorg Onderzoek Nederland en Medische Wetenschappen (ZonMw)

COVID19 Outcomes in Older People (COOP) study (project number 10430102110005 under the COVID-19 programme)

University Network of the Care sector South-Holland (UNC-ZH) (grant number 640001003)

UK National Institute of Health Research Academic Research Collaboration-East Midlands (ARC-EM)

History

Comments

The original article is available at https://academic.oup.com/

Published Citation

van Tol LS, et al. Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life. Age Ageing. 2024;53(5):afae084.

Publication Date

9 May 2024

PubMed ID

38725361

Department/Unit

  • Beaumont Hospital

Publisher

Oxford University Press

Version

  • Published Version (Version of Record)