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Potential of ethenone (ketene) to contribute to electronic cigarette, or vaping, product use-associated lung injury

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journal contribution
posted on 22.11.2021, 14:09 by Kathleen R Attfield, Wenhao Chen, Kristin J Cummings, Peyton Jacob, Donal O'SheaDonal O'Shea, Jeff Wagner, Ping Wang, Jefferson Fowles

In 2019, the United States experienced an unprecedented outbreak of electronic cigarette (e-cigarette), or vaping, product use– associated lung injury (EVALI). Although reports of lipidladen macrophages in BAL fluid raised the possibility that EVALI represented exogenous lipoid pneumonia, case series that focused on histopathology found patterns of acute lung injury, including diffuse alveolar damage and organizing pneumonia, often with bronchiolitis. Thus, the available evidence to date suggests the outbreak is characterized by an airway-centered chemical pneumonitis rather than acute exogenous lipoid pneumonia.

History

Comments

Originally Published in: Attfield KR, Chen W, Cummings KJ, Jacob P 3rd, O'Shea DF, Wagner J, Wang P, Fowles J. Potential of ethenone (ketene) to contribute to electronic cigarette, or vaping, product use-associated lung injury. Am J Respir Crit Care Med. 2020;202(8):1187-1189. doi:10.1164/rccm.202003-0654LE. Copyright © 2020 by the American Thoracic Society The final publication is available at http://www.atsjournals.org

Published Citation

Attfield KR. et al. Potential of ethenone (ketene) to contribute to electronic cigarette, or vaping, product use-associated lung injury. Am J Respir Crit Care Med. 2020;202(8):1187-1189.

Publication Date

18 June 2020

PubMed ID

32551843

Department/Unit

  • Chemistry

Research Area

  • Cancer
  • Surgical Science and Practice
  • Chemistry and Pharmaceutical Sciences

Publisher

American Thoracic Society

Version

  • Accepted Version (Postprint)