Cannon 2020 Prenatal and perinatal complications in the development of psychosis canaries in the coalmine.pdf (565.23 kB)
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Prenatal and perinatal complications in the development of psychosis: canaries in the coalmine

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journal contribution
posted on 28.01.2022, 15:09 authored by Mary CannonMary Cannon, Colm HealyColm Healy, Mary ClarkeMary Clarke, David CotterDavid Cotter

Although first suggested as early as the 1930s, the study of obstetric complications as risk factors for later psychotic disorders came to the fore in the late 1980s, when proponents of the neurodevelopmental aetiological model of schizophrenia cited the association between obstetric adversity and later schizophrenia as an essential building block for this theoretical approach. A meta-analytic review of this literature in 2002 concluded that no specific obstetric complications were associated with schizophrenia– rather a host of prenatal and perinatal risk factors of small effect size (typically with odds ratios [ORs] of less than 2).


Funding

European Research Council Consolidator Award (iHEAR) 724809

Irish Research Council

Health Research Board (Ireland)

History

Comments

The original article is available at https://www.thelancet.com/

Published Citation

Cannon M, Healy C, Clarke MC, Cotter D. Prenatal and perinatal complications in the development of psychosis: canaries in the coalmine. Lancet Psychiatry. 2020;7(5):372-373

Publication Date

24 March 2020

PubMed ID

32220287

Department/Unit

  • Beaumont Hospital
  • Health Psychology
  • Psychiatry

Research Area

  • Population Health and Health Services
  • Neurological and Psychiatric Disorders

Publisher

Elsevier BV

Version

  • Accepted Version (Postprint)