Royal College of Surgeons in Ireland
Browse
SG OUD AEM E&T Clean Version_Updated.pdf (517.78 kB)

Sex, gender, and the opioid epidemic: crucial implications for acute care.

Download (517.78 kB)
journal contribution
posted on 2022-09-05, 16:51 authored by Lauren A. Walter, Savannah Bunnell, Kathryn Wiesendanger, Alyson J. McGregor

Introduction: The opioid epidemic continues to escalate in the United States, exacerbated significantly by the COVID-19 pandemic. Necessary steps in acute care medicine to expand efforts to combat this epidemic involve increased emergency department engagement of patients with opioid use disorder (OUD) and an incorporation of evolving sex- and gender-based factors that affect this disease presentation and management course.

Methods & aims: An ever-increasing amount of peer-reviewed, evidence-based literature has shed light on the important biologic and sociocultural variables, specifically sex and gender, which impact OUD trajectory and outcomes. As a collaborative effort of the Sex and Gender in Emergency Medicine (SGEM) Interest Group, a community within the Society for Academic Emergency Medicine (SAEM), we sought to consider, review, and summarize clinically pertinent information as a comprehensive introduction to this topic for the emergency medicine (EM) clinician and educator.

Results: A selected overview of current evidence-based data and publications, to include current epidemiologic trends, opioid-based physiology and pathophysiology, as well as opioid use disorder management and outcomes, through a sex- and gender-based lens, was reviewed and included in this summary. Also discussed are implications and recommendations for EM educators seeking insight and resources for continuing, graduate, and/or undergraduate education on this topic.

Conclusion: Incorporation of emerging sex- and gender-specific scientific knowledge into clinical context represents a critical link to effective management of the OUD patient in the ED. Similarly, integration of this information into EM education represents an essential step for both sex- and gender-based medicine and opioid-specific training.

History

Comments

"This is the peer reviewed version of the following article: Walter LA, Bunnell S, Wiesendanger K, McGregor AJ. Sex, gender, and the opioid epidemic: crucial implications for acute care. AEM Educ Train. 2022;6(Suppl 1):S64-S70, which has been published in final form at https://doi.org/10.1002/aet2.10756. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited."

Published Citation

Walter LA, Bunnell S, Wiesendanger K, McGregor AJ. Sex, gender, and the opioid epidemic: crucial implications for acute care. AEM Educ Train. 2022;6(Suppl 1):S64-S70

Publication Date

23 June 2022

PubMed ID

35783078

Department/Unit

  • Undergraduate Research

Publisher

John Wiley & Sons, Inc.

Version

  • Accepted Version (Postprint)