Royal College of Surgeons in Ireland
The Role of Platelets in Viral Hemorrhagic Fevers.pdf (1.49 MB)

The Role of Platelets in Viral Hemorrhagic Fevers

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Version 2 2021-11-24, 15:47
Version 1 2019-11-22, 16:23
journal contribution
posted on 2021-11-24, 15:47 authored by Dermot CoxDermot Cox, Maria S. Salvato, Juan Carlos Zapata

Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe thrombocytopenia. Here, we review the literature on viral hemorrhagic fever and discuss the role played by platelets in the coagulopathy. We also discuss the possibility of using anti-platelet agents to moderate the coagulopathy, a strategy that might have a role to play in treating patients infected by these viruses.



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Published Citation

Cox D, Salvato M, Zapata JC. The Role of Platelets in Viral Hemorrhagic Fevers. Journal of Bioterrorism & Biodefense S12:003. doi: 10.4172/2157-2526.S12-003

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  • School of Pharmacy and Biomolecular Sciences