Royal College of Surgeons in Ireland
The interaction of bacterial pathogens with platelets..pdf (625.58 kB)

The interaction of bacterial pathogens with platelets.

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Version 2 2022-02-25, 15:38
Version 1 2019-11-22, 16:14
journal contribution
posted on 2022-02-25, 15:38 authored by J Ross Fitzgerald, Timothy J. Foster, Dermot CoxDermot Cox

In recent years, the frequency of serious cardiovascular infections such as endocarditis has increased, particularly in association with nosocomially acquired antibiotic-resistant pathogens. Growing evidence suggests a crucial role for the interaction of bacteria with human platelets in the pathogenesis of cardiovascular infections. Here, we review the nature of the interactions between platelets and bacteria, and the role of these interactions in the pathogenesis of endocarditis and other cardiovascular diseases.



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Fitzgerald J R, Cox D, Foster T J. The interaction of bacterial pathogens with platelets. Nature Review Microbiology 2006;4(6):445-57.

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  • School of Pharmacy and Biomolecular Sciences