Royal College of Surgeons in Ireland
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Vitamin D deficiency in schizophrenia implications for COVID-19 infection

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journal contribution
posted on 2022-03-16, 12:10 authored by Dylan Viani-Walsh, Sarah Kennedy-Williams, D. Taylor, F. Gaughran, John LallyJohn Lally
Vitamin D deficiency is associated with an increased risk of acute respiratory infection. There is an excess of respiratory infections and deaths in schizophrenia, a condition where vitamin D deficiency is especially prevalent. This potentially offers a modifiable risk factor to reduce the risk for and the severity of respiratory infection in people with schizophrenia, although there is as yet no evidence regarding the risk of COVID-19. In this narrative review, we describe the prevalence of vitamin D deficiency in schizophrenia, report the research examining the relationship between vitamin D levels and COVID-19 and discuss the associations between vitamin D deficiency and respiratory infection, including its immunomodulatory mechanism of action.



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Published Citation

Viani-Walsh D, Kennedy-Williams S, Taylor D, Gaughran F, Lally J. Vitamin D deficiency in schizophrenia implications for COVID-19 infection. Ir J Psychol Med. 2020;38(4):278-287.

Publication Date

11 September 2020

PubMed ID



  • Undergraduate Research
  • Psychiatry


Cambridge University Press


  • Published Version (Version of Record)