Vitamin D in schizophrenia and depression: a clinical review
Evidence from preclinical and clinical studies supports a role for vitamin D deficiency in many mental disorders. In this review, we discuss the role of vitamin D in the aetiology and treatment of schizophrenia and depression and their physical health comorbidities. Although observational studies support a potential association between vitamin D and schizophrenia and depression, sufficient high-quality evidence from clinical trials does not yet exist to establish a place for vitamin D supplementation in optimising clinical response or promoting physical health. Completed randomised controlled trials are needed to provide insights into the efficacy and safety of vitamin D in the management of mental disorders.
CommentsThe original article is available at https://www.cambridge.org/core/journals/bjpsych-advances
Published CitationLally J, Gaughran, F. Vitamin D in schizophrenia and depression: A clinical review. BJPsych Advances. 2019;25(4):240-248.
Publication Date17 April 2019
- Neurological and Psychiatric Disorders
PublisherCambridge University Press
- Accepted Version (Postprint)