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Development of Novel Double Network Polypeptide-Based Hydrogels with Enhanced Mechanical Properties

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thesis
posted on 13.12.2021, 16:06 authored by Shona O'Brien
This chapter introduces the concept of physical and covalent hydrogels derived from both natural and synthetic starting materials. In addition the idea of double network hydrogels as a methodology to modulate the mechanical strength of hydrogel networks is presented and discussed.
In the latter half of this chapter relevant polypeptide-based hydrogels are discussed. Furthermore, synthetic approaches utilised to achieve such materials; namely N-carboxyanhydride (NCA) ring-opening polymerisation
(ROP) of functional NCA monomers and post-polymerisation crosslinking are introduced.

History

First Supervisor

Prof. Andreas Heise

Second Supervisor

Prof. Sally-Ann Cryan

Comments

Submitted for the Award of Doctor of Philosophy to the Royal College of Surgeons in Ireland, 2020

Published Citation

O'Brien S,. Development of Novel Double Network Polypeptide-Based Hydrogels with Enhanced Mechanical Properties [PhD Thesis] Dublin: Royal College of Surgeons in Ireland; 2020

Degree Name

Doctor of Philosophy (PhD)

Date of award

31/05/2020

Programme

  • Doctor of Philosophy (PhD)

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