Royal College of Surgeons in Ireland
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Development of Novel Hydrogels for Application in Therapeutic Delivery

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thesis
posted on 2019-11-22, 17:40 authored by Robert D. Murphy

This chapter will detail the beginnings and current state of NCA derived synthetic polypeptides, the role of multifunctional initiators in the development of complex star shaped polypeptide architectures and their associated properties, the synthetic approaches undertaken for the design of hydrogelating materials from the NCA ring opening polymerisation; detailing the dependence on amino acid composition and architecture; followed by a brief introduction to 3D printing and its potential relevance in the fabrication of polypeptide hydrogels.

History

First Supervisor

Professor Andreas Heise

Second Supervisor

Professor Sally-Ann Cryan

Comments

A thesis submitted for the degree of Doctor of Philosophy from the Royal College of Surgeons in Ireland in 2018.

Published Citation

Murphy RD. Development of Novel Hydrogels for Application in Therapeutic Delivery [PhD Thesis]. Dublin: Royal College of Surgeons in Ireland; 2018.

Degree Name

  • Doctor of Philosophy (PhD)

Date of award

2018-11-30

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