Development of Novel Hydrogels for Application in Therapeutic Delivery
This chapter will detail the beginnings and current state of NCA derived synthetic polypeptides, the role of multifunctional initiators in the development of complex star shaped polypeptide architectures and their associated properties, the synthetic approaches undertaken for the design of hydrogelating materials from the NCA ring opening polymerisation; detailing the dependence on amino acid composition and architecture; followed by a brief introduction to 3D printing and its potential relevance in the fabrication of polypeptide hydrogels.
First SupervisorProfessor Andreas Heise
Second SupervisorProfessor Sally-Ann Cryan
CommentsA thesis submitted for the degree of Doctor of Philosophy from the Royal College of Surgeons in Ireland in 2018.
Published CitationMurphy RD. Development of Novel Hydrogels for Application in Therapeutic Delivery [PhD Thesis]. Dublin: Royal College of Surgeons in Ireland; 2018.
- Doctor of Philosophy (PhD)