Progresses on the development of stereoselective [2+2], [2+3] and [4+3] cycloadditions.
thesisposted on 2019-11-22, 17:46 authored by Paolo Disetti
The present work dealt with the preparation of some key intermediates and their use for the generation of chemical diversity. In Chapter 2 we described a Catalytic Asymmetric Conjugate Addition of isocyanoacetates to 4-nitro-5-styrylisoxmles. In Chapter 3 we described a new strategy for the preparation of medium sized oxepanes oxocanes and oxonanes. In Chapter 4 we described a novel route to alkene-hctionalised monobactams and their potential in diversity oriented synthesis is still in progress.
First SupervisorProfessor Mauro Adamo.
CommentsA thesis submitted to the Royal College of Surgeons in Ireland for the degree of Doctor of Philosophy from the National University of Ireland in 2011.
Published CitationDisetti, P. Progresses on the development of stereoselective [2+2], [2+3] and [4+3] cycloadditions. [PhD Thesis]. Dublin : Royal College of Surgeons in Ireland, 2011.
- Doctor of Philosophy (PhD)