Biological sciences

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Innate immunity in cystic fibrosis: varied effects of CFTR modulator therapy on cell-to-cell communication

Innate immunity in cystic fibrosis: varied effects of CFTR modulator therapy on cell-to-cell communication

journal contribution posted on 2025-05-08

Circulating miRNAs are associated with successful bone regeneration

Circulating miRNAs are associated with successful bone regeneration

journal contribution posted on 2025-05-07

PARP inhibitors in the neoadjuvant setting; a comprehensive overview of the rationale for their use, past and ongoing clinical trials

PARP inhibitors in the neoadjuvant setting; a comprehensive overview of the rationale for their use, past and ongoing clinical trials

journal contribution posted on 2025-05-01

Expanding the therapeutic role of highly purified cannabidiol in monogenic epilepsies: a multicenter real-world study

Expanding the therapeutic role of highly purified cannabidiol in monogenic epilepsies: a multicenter real-world study

journal contribution posted on 2025-04-25

Acute kidney injury in late-onset neonatal bacteraemia: the role of the neonatal sequential organ failure assessment tool in predicting kidney injury

Acute kidney injury in late-onset neonatal bacteraemia: the role of the neonatal sequential organ failure assessment tool in predicting kidney injury

journal contribution posted on 2025-04-08

Donor and recipient polygenic risk scores influence kidney transplant function

Donor and recipient polygenic risk scores influence kidney transplant function

journal contribution posted on 2025-04-08

FILES UNDER EMBARGO

Decoy oligonucleotides targeting NF-κB: a promising therapeutic approach for inflammatory diseases

journal contribution posted on 2025-03-28

Presepsin, procalcitonin, interleukin-6, and high-sensitivity C-reactive protein for predicting bacterial DNAaemia among patients with sepsis

Presepsin, procalcitonin, interleukin-6, and high-sensitivity C-reactive protein for predicting bacterial DNAaemia among patients with sepsis

journal contribution posted on 2025-03-25

Polygenic risk scores for eGFR are associated with age at kidney failure

Polygenic risk scores for eGFR are associated with age at kidney failure

journal contribution posted on 2025-03-25

Hypoxia-inducible factor and cellular senescence in pulmonary aging and disease

Hypoxia-inducible factor and cellular senescence in pulmonary aging and disease

journal contribution posted on 2025-03-25

Advancing the understanding and treatment of lung pathologies associated with alpha 1 antitrypsin deficiency

Advancing the understanding and treatment of lung pathologies associated with alpha 1 antitrypsin deficiency

journal contribution posted on 2025-03-11

Green synthesis of metal nanoparticles using <i>Cinnamomum</i>-based extracts and their applications

Green synthesis of metal nanoparticles using Cinnamomum-based extracts and their applications

journal contribution posted on 2025-03-11

The impact of a secondary, rare, non-pathogenic <i>PKD1 </i>variant on disease progression in autosomal dominant polycystic kidney disease

The impact of a secondary, rare, non-pathogenic PKD1 variant on disease progression in autosomal dominant polycystic kidney disease

journal contribution posted on 2025-03-10

Case report: hypoalbuminaemia in THE

Case report: hypoalbuminaemia in THE

journal contribution posted on 2025-03-10

Eight-fold increased COVID-19 mortality in autosomal dominant tubulointerstitial kidney disease due to<i> MUC1</i> mutations: an observational study

Eight-fold increased COVID-19 mortality in autosomal dominant tubulointerstitial kidney disease due to MUC1 mutations: an observational study

journal contribution posted on 2025-03-10

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Phenotypic outcomes of PKD1 compared with non-PKD1 genetically confirmed autosomal dominant polycystic kidney disease

journal contribution posted on 2025-03-07

Preserving the antimicrobial arsenal: exploring alternatives to carbapenems in ESBL battles within the southeast of Ireland

Preserving the antimicrobial arsenal: exploring alternatives to carbapenems in ESBL battles within the southeast of Ireland

journal contribution posted on 2025-03-07

Tissue factor-dependent colitogenic CD4<sup>+</sup> T cell thrombogenicity is regulated by activated protein C signalling

Tissue factor-dependent colitogenic CD4⁺ T cell thrombogenicity is regulated by activated protein C signalling

journal contribution posted on 2025-02-26

Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling

Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling

preprint posted on 2025-02-26

The role of osteoprotegerin in breast cancer: genetic variations, tumorigenic pathways, and therapeutic potential

The role of osteoprotegerin in breast cancer: genetic variations, tumorigenic pathways, and therapeutic potential

journal contribution posted on 2025-02-25

Multiomic sequencing reveals distinctive gene expression and epigenetic alterations associated with primary sclerosing cholangitis development in treatment-naïve pediatric ulcerative colitis

Multiomic sequencing reveals distinctive gene expression and epigenetic alterations associated with primary sclerosing cholangitis development in treatment-naïve pediatric ulcerative colitis

journal contribution posted on 2025-02-19

Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes [verison 2]

Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes [verison 2]

preprint posted on 2025-02-13

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TLR/NLRP3 inflammasome signaling pathways as a main target in frailty, cachexia and sarcopenia

journal contribution posted on 2025-02-12

Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine

Metabolic reprogramming of macrophages by PKM2 promotes IL-10 production via adenosine

journal contribution posted on 2025-02-11

Catalytic degradation and antibacterial activity of cinnamon-mediated green synthesized silver nanoparticles loaded on alginate beads

Catalytic degradation and antibacterial activity of cinnamon-mediated green synthesized silver nanoparticles loaded on alginate beads

journal contribution posted on 2025-02-10

The role of the liver in the pathophysiology of PCOS: a literature review

The role of the liver in the pathophysiology of PCOS: a literature review

journal contribution posted on 2025-02-10

The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance

The importance of microbiology reference laboratories and adequate funding for infectious disease surveillance

journal contribution posted on 2025-02-10

Effects of ALS-associated 5’tiRNA^Gly-GCC on the transcriptomic and proteomic profile of primary neurons in vitro

journal contribution posted on 2025-02-07

Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice

Sphingosine 1-phosphate receptor 1signaling in macrophages reduces atherosclerosis in LDL receptor-deficient mice

journal contribution posted on 2025-02-07

Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency

Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency

journal contribution posted on 2025-02-06

Novel cyclometalated iridium (III) complexes as antibacterial agents for photodynamic inactivation

Novel cyclometalated iridium (III) complexes as antibacterial agents for photodynamic inactivation

journal contribution posted on 2025-02-06

Decoding the genetic landscape of autism: a comprehensive review

Decoding the genetic landscape of autism: a comprehensive review

journal contribution posted on 2025-02-06

Microbial enzymes as powerful natural anti-biofilm candidates

Microbial enzymes as powerful natural anti-biofilm candidates

journal contribution posted on 2025-02-06

Discovery of Novel Genes and Mechanisms in Rare Neuroendocrine Diseases

Discovery of Novel Genes and Mechanisms in Rare Neuroendocrine Diseases

thesis posted on 2025-02-05

Adrian Francis Daly

The emerging role of p21 in diabetes and related metabolic disorders

The emerging role of p21 in diabetes and related metabolic disorders

journal contribution posted on 2025-02-04

Response to "Understanding familial variability in ADPKD : a comprehensive approach integrating genetics, hormones, and lifestyle for tailored management"

Response to "Understanding familial variability in ADPKD : a comprehensive approach integrating genetics, hormones, and lifestyle for tailored management"

journal contribution posted on 2025-01-30

Similarity of phenotype in three male patients with the c.320A>G variant in <i>ALG13</i>: possible genotype-phenotype correlation

Similarity of phenotype in three male patients with the c.320A>G variant in ALG13: possible genotype-phenotype correlation

journal contribution posted on 2025-01-28

Gut microbial taxonomy and its role as a biomarker in aortic diseases a systematic review and future perspectives

Gut microbial taxonomy and its role as a biomarker in aortic diseases a systematic review and future perspectives

journal contribution posted on 2025-01-27

FILES UNDER EMBARGO

Effects of dietary curcumin on gene expression: an analysis of transcriptomic data in mice

journal contribution posted on 2025-01-22

Time-of-day control of mitochondria regulates NLRP3 inflammasome activation in macrophages

Time-of-day control of mitochondria regulates NLRP3 inflammasome activation in macrophages

journal contribution posted on 2025-01-21